Chemistry
We carry out a broad range of chemical reactions at Lianhetech Seal Sands. With a wide variety of equipment, long experience in handling hazardous materials and processes safely, and on-site process safety testing we are set up to deal with most chemistries run at manufacturing scale.
Although by no means comprehensive, the following examples demonstrate a unique breadth of chemical experience on a commercial scale:
- Sulphur Chemistry
- Halogenation
- Reductions
- Oxidation
- Low Temperature Capability/Organometallic Reactions
- Ozonolysis
- Other Hazardous Reagents/Reactions
Development
We have five fully-equipped Development Laboratories, each fitted with large (2.0 to 2.3 m) fume cupboards and at least one walk-in fume cupboard for larger scale plant mimic equipment.
One laboratory is dedicated to Process Safety testing and is equipped with a Mettler™ RC1 Calorimeter, ARC, Carius tube, flash point and DSC apparatus.
We also have autoclave/pressure reaction capabilities and a number of automated reactors (Mettler™ LabMax) and multi-reactors (Argonaut) units as well as Radley’s equipment for process optimisation and development of reaction conditions.
The Development Laboratories are comprehensively equipped with analytical equipment – each having a number of GC and HPLC machines (including (GCMS and LCMS), which allows for rapid analysis and real-time monitoring of reactions.
Hazards Management
Lianhetech Seal Sands has a proven track record in the safe management of hazardous chemical processes.
Our expertise, flexible plant and broad permits ensure our ability to deliver the most challenging chemical solutions.
The implementation of any change is based on assessment by a comprehensive hazard management system.
Before introduction of any new substance a process is followed in a dedicated hazards testing laboratory – equipped with state of the art reaction calorimetery, such as RC1 with RTCal™, Differential Scanning Calorimetry, Carius Tube test and flash point determination.
Accelerated Rate Calorimetry (ARC) evaluates each reaction step to identify the basis and envelope of safety.
The site is Top-Tier COMAH (Seveso III) compliant, has a broad environmental permit and similarly has extensive consents in place to allow us to handle a broad range of substances at a range of scales.
Quality Control
The Quality Control (QC) department operates on a 24 hour basis. Analysis of raw material, in-process, final product and environmental samples is undertaken to the appropriate ISO 9001 certified and cGMP standards to meet our customers’ requirements.
Temperature and humidity-controlled sample storage is available for product stability testing. The department is equipped with 10 GCs, 20 HPLCs, a 400 MHz NMR, as well as an ion chromatograph, FTIR, UV and KF and the usual wet techniques. To support the waste management facilities there is also analysis for chemical oxygen demand (COD) and biological oxygen demand (BOD).